articleNucleic Acids ResearchDec 28, 2005GOLD OA

BioGRID: a general repository for interaction datasets

Princess Margaret Cancer Centre · Ontario Institute for Cancer Research

PubMed
Indexed incrossrefdatacitedoajpubmed

Abstract

Access to unified datasets of protein and genetic interactions is critical for interrogation of gene/protein function and analysis of global network properties. BioGRID is a freely accessible database of physical and genetic interactions available at http://www.thebiogrid.org. BioGRID release version 2.0 includes >116 000 interactions from Saccharomyces cerevisiae, Caenorhabditis elegans, Drosophila melanogaster and Homo sapiens. Over 30 000 interactions have recently been added from 5778 sources through exhaustive curation of the Saccharomyces cerevisiae primary literature. An internally hyper-linked web interface allows for rapid search and retrieval of interaction data. Full or user-defined datasets are…

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Topics & keywords

Keywords
  • Biology
  • Graphical user interface
  • Visualization
  • Computational biology
  • Gene interaction
  • Drosophila melanogaster
  • Saccharomyces cerevisiae
  • User interface
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