Ewing Sarcoma: Current Management and Future Approaches Through Collaboration

Ewing sarcoma (ES) is an aggressive sarcoma of bone and soft tissue occurring at any age with a peak incidence in adolescents and young adults. The treatment of ES relies on a multidisciplinary approach, coupling risk-adapted intensive neoadjuvant and adjuvant chemotherapies with surgery and/or radiotherapy for control of the primary site and possible metastatic disease. The optimization of ES multimodality therapeutic strategies has resulted from the efforts of several national and international groups in Europe and North America and from cooperation between pediatric and medical oncologists. Successive first-line trials addressed the efficacy of various cyclic combinations of drugs incorporating doxorubicin,…

• CR
  Cancer Research Institute
• NC
  National Cancer Research Institute
• CR
  Cancer Research UK
• NI
  National Institute for Health and Care Research
• UC
  University College London
• BF
  Bundesministerium für Bildung und Forschung

  Awards: 01ER0807, 01KT1310, 01GM0869
• EO
  European Organisation for Research and Treatment of Cancer
• DK
  Deutsche Krebshilfe

  Awards: DKH 108128, 108128
• B
  Barncancerfonden
• U
  Unicancer
• FH
  FP7 Health

  Award: 602030