articleDevelopmental Medicine & Child NeurologyJan 24, 2002GOLD OA

Development of cortical and subcortical brain structures in childhood and adolescence: a structural MRI study

University of California, Los Angeles · University of California San Diego Medical Center · +1 more institution

PubMed
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Abstract

The purpose of the present study was to describe in greater anatomical detail the changes in brain structure that occur during maturation between childhood and adolescence. High-resolution MRI, tissue classification, and anatomical segmentation of cortical and subcortical regions were used in a sample of 35 normally developing children and adolescents between 7 and 16 years of age (mean age 11 years; 20 males, 15 females). Each cortical and subcortical measure was examined for age and sex effects on raw volumes and on the measures as proportions of total supratentorial cranial volume. Results indicate age-related increases in total supratentorial cranial volume and raw and proportional increases in total…

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