articleTherapeutic Advances in GastroenterologyMar 26, 2013GREEN OA

Role of the gut microbiota in health and chronic gastrointestinal disease: understanding a hidden metabolic organ

Teagasc - The Irish Agriculture and Food Development Authority · University College Cork

PubMed
Indexed incrossrefdoajpubmed

Abstract

The human gut microbiota has become the subject of extensive research in recent years and our knowledge of the resident species and their potential functional capacity is rapidly growing. Our gut harbours a complex community of over 100 trillion microbial cells which influence human physiology, metabolism, nutrition and immune function while disruption to the gut microbiota has been linked with gastrointestinal conditions such as inflammatory bowel disease and obesity. Here, we review the many significant recent studies that have centred on further enhancing our understanding of the complexity of intestinal communities as well as their genetic and metabolic potential. These have provided important information…

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Authors

2

Topics & keywords

Keywords
  • Gut flora
  • Microbiome
  • Gut microbiome
  • Gut–brain axis
  • Disease
  • Immune system
  • Inflammatory bowel disease
  • Gastrointestinal tract
UN Sustainable Development Goals
  • Zero hunger
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