Amygdala and Ventromedial Prefrontal Cortex Are Inversely Coupled during Regulation of Negative Affect and Predict the Diurnal Pattern of Cortisol Secretion among Older Adults
University of Wisconsin System · Imaging, Brain, and Neuropsychiatry · +2 more institutions
Abstract
Among younger adults, the ability to willfully regulate negative affect, enabling effective responses to stressful experiences, engages regions of prefrontal cortex (PFC) and the amygdala. Because regions of PFC and the amygdala are known to influence the hypothalamic-pituitary-adrenal axis, here we test whether PFC and amygdala responses during emotion regulation predict the diurnal pattern of salivary cortisol secretion. We also test whether PFC and amygdala regions are engaged during emotion regulation in older (62- to 64-year-old) rather than younger individuals. We measured brain activity using functional magnetic resonance imaging as participants regulated (increased or decreased) their affective…
Citation impact
- FWCI
- 16.11
- Percentile
- 100%
- References
- 44
Authors
11- HLHeather L. UrryCorresponding
University of Wisconsin System, Imaging, Brain, and Neuropsychiatry, Institute of Psychology
- CMCarien M. van Reekum
Imaging, Brain, and Neuropsychiatry, Institute of Psychology
- TJTom Johnstone
Imaging, Brain, and Neuropsychiatry
- NHNed H. Kalin
Institute of Psychology
- MEMarchell E. Thurow
Institute of Psychology
Topics & keywords
- Amygdala
- Ventromedial prefrontal cortex
- Psychology
- Prefrontal cortex
- Affect (linguistics)
- Functional magnetic resonance imaging
- Neuroscience
- Endocrinology