Rfam 11.0: 10 years of RNA families
Wellcome Sanger Institute · Howard Hughes Medical Institute · +2 more institutions
Abstract
The Rfam database (available via the website at http://rfam.sanger.ac.uk and through our mirror at http://rfam.janelia.org) is a collection of non-coding RNA families, primarily RNAs with a conserved RNA secondary structure, including both RNA genes and mRNA cis-regulatory elements. Each family is represented by a multiple sequence alignment, predicted secondary structure and covariance model. Here we discuss updates to the database in the latest release, Rfam 11.0, including the introduction of genome-based alignments for large families, the introduction of the Rfam Biomart as well as other user interface improvements. Rfam is available under the Creative Commons Zero license.
Citation impact
- FWCI
- 46.48
- Percentile
- 100%
- References
- 20
Authors
9Topics & keywords
- Biology
- Computational biology
- RNA
- Angiogenin
- Genetics
- Gene