articleNew England Journal of MedicineMar 26, 2012BRONZE OA

Two-Year Outcomes after Transcatheter or Surgical Aortic-Valve Replacement

NewYork–Presbyterian Hospital · Columbia University Irving Medical Center · +22 more institutions

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Abstract

Background

The Placement of Aortic Transcatheter Valves (PARTNER) trial showed that among high-risk patients with aortic stenosis, the 1-year survival rates are similar with transcatheter aortic-valve replacement (TAVR) and surgical replacement. However, longer-term follow-up is necessary to determine whether TAVR has prolonged benefits.

Methods

At 25 centers, we randomly assigned 699 high-risk patients with severe aortic stenosis to undergo either surgical aortic-valve replacement or TAVR. All patients were followed for at least 2 years, with assessment of clinical outcomes and echocardiographic evaluation.

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