Post‐traumatic osteoarthritis: Improved understanding and opportunities for early intervention

Even with current treatments of acute joint injuries, more than 40% of people who suffer significant ligament or meniscus tears, or articular surface injuries, will develop osteoarthritis (OA). Correspondingly, 12% or more of all patients with lower extremity OA have a history of joint injury. Recent research suggests that acute joint damage that occurs at the time of an injury initiates a sequence of events that can lead to progressive articular surface damage. New molecular interventions, combined with evolving surgical methods, aim to minimize or prevent progressive tissue damage triggered by joint injury. Seizing the potential for progress in the treatment of joint injuries to forestall OA will depend on…

• AF
  Arthritis Foundation

  Awards: AG15768, AR48182, AR50245, AR48852
• NC
  NFL Charities
• OR
  Orthopaedic Research and Education Foundation
• RU
  Rush University
• AF
  AO Foundation
• NI
  National Institutes of Health

  Awards: AG15768, AR48182, AR39239, AR48852, AR50245
• NI
  National Institute on Aging

  Award: AG15768
• NI
  National Institute of Arthritis and Musculoskeletal and Skin Diseases

  Awards: AG15768, AR50245