articleJournal of the American Society of NephrologyApr 6, 2006Closed access

Fibroblast Growth Factor 23 Is a Counter-Regulatory Phosphaturic Hormone for Vitamin D

SLShiguang LiuWTWen TangJZJianping ZhouJRJason R. StubbsQLQiang Luo

University of Kansas Medical Center

PubMed
Indexed incrossrefpubmed

Abstract

The regulation of the phosphaturic factor fibroblast growth factor 23 (FGF23) is not well understood. It was found that administration of 1,25-dihydroxyvitamin D(3) (1,25[OH](2)D(3)) to mice rapidly increased serum FGF23 concentrations from a basal level of 90.6 +/- 8.1 to 213.8 +/- 14.6 pg/ml at 8 h (mean +/- SEM; P

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Topics & keywords

Topics
Keywords
  • Endocrinology
  • Internal medicine
  • Parathyroid hormone
  • Fibroblast growth factor 23
  • Vitamin D and neurology
  • PHEX
  • Vitamin
  • Fibroblast growth factor
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