articleJNCI Journal of the National Cancer InstituteJun 14, 2005BRONZE OA

Meat, Fish, and Colorectal Cancer Risk: The European Prospective Investigation into Cancer and Nutrition

Centre international de recherche sur le cancer · Institut Català d'Ornitologia · +26 more institutions

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Abstract

Background

Current evidence suggests that high red meat intake is associated with increased colorectal cancer risk. High fish intake may be associated with a decreased risk, but the existing evidence is less convincing.

Methods

We prospectively followed 478 040 men and women from 10 European countries who were free of cancer at enrollment between 1992 and 1998. Information on diet and lifestyle was collected at baseline. After a mean follow-up of 4.8 years, 1329 incident colorectal cancers were documented. We examined the relationship between intakes of red and processed meat, poultry, and fish and colorectal cancer risk using a proportional hazards model adjusted for age, sex, energy (nonfat and fat sources), height, weight, work-related physical activity, smoking status, dietary fiber and folate, and alcohol consumption, stratified by center. A calibration substudy based on 36 994 subjects was used to correct hazard ratios (HRs) and 95% confidence intervals (CIs) for diet measurement errors. All statistical tests were two-sided.

Citation impact

863
total citations
FWCI
60.90
Percentile
100%
References
55
Citations per year

Authors

46

Topics & keywords

Keywords
  • Red meat
  • Medicine
  • Colorectal cancer
  • Hazard ratio
  • Cancer
  • Prospective cohort study
  • European Prospective Investigation into Cancer and Nutrition
  • Confidence interval
UN Sustainable Development Goals
  • Good health and well-being
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