articleThe Journals of Gerontology Series ADec 3, 2012GREEN OA

Modeling the Rate of Senescence: Can Estimated Biological Age Predict Mortality More Accurately Than Chronological Age?

MEMorgan E. Levine

University of Southern California

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Abstract

Biological age (BA) is useful for examining differences in aging rates. Nevertheless, little consensus exists regarding optimal methods for calculating BA. The aim of this study is to compare the predictive ability of five BA algorithms. The sample included 9,389 persons, aged 30-75 years, from National Health and Nutrition Examination Survey III. During the 18-year follow-up, 1,843 deaths were counted. Each BA algorithm was compared with chronological age on the basis of predictive sensitivity and strength of association with mortality. Results found that the Klemera and Doubal method was the most reliable predictor of mortality and performed significantly better than chronological age. Furthermore, when…

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Topics & keywords

Topics
Keywords
  • Biological age
  • National Health and Nutrition Examination Survey
  • Demography
  • Senescence
  • Gerontology
  • Mortality rate
  • Age groups
  • Medicine
UN Sustainable Development Goals
  • Good health and well-being
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