Preexposure Prophylaxis for HIV Infection among African Women
Family Health International 360 · Setshaba Research Centre · +7 more institutions
Indexed incrossrefpubmed
Abstract
Background
Preexposure prophylaxis with antiretroviral drugs has been effective in the prevention of human immunodeficiency virus (HIV) infection in some trials but not in others.
Methods
In this randomized, double-blind, placebo-controlled trial, we assigned 2120 HIV-negative women in Kenya, South Africa, and Tanzania to receive either a combination of tenofovir disoproxil fumarate and emtricitabine (TDF-FTC) or placebo once daily. The primary objective was to assess the effectiveness of TDF-FTC in preventing HIV acquisition and to evaluate safety.
Citation impact
1,614
total citations
- FWCI
- 90.38
- Percentile
- 100%
- References
- 6
Citations per year
Authors
29Topics & keywords
Topics
Keywords
- Medicine
- Placebo
- Emtricitabine
- Discontinuation
- Internal medicine
- Hazard ratio
- Pill
- Pre-exposure prophylaxis
UN Sustainable Development Goals
- Good health and well-being
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