International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and Classification of Adenosine Receptors—An Update
National Institute of Diabetes and Digestive and Kidney Diseases · University of Bonn · +4 more institutions
Abstract
In the 10 years since our previous International Union of Basic and Clinical Pharmacology report on the nomenclature and classification of adenosine receptors, no developments have led to major changes in the recommendations. However, there have been so many other developments that an update is needed. The fact that the structure of one of the adenosine receptors has recently been solved has already led to new ways of in silico screening of ligands. The evidence that adenosine receptors can form homo- and heteromultimers has accumulated, but the functional significance of such complexes remains unclear. The availability of mice with genetic modification of all the adenosine receptors has led to a clarification…
Citation impact
- FWCI
- 70.63
- Percentile
- 100%
- References
- 297
Authors
5- BBBertil B. FredholmCorresponding
National Institute of Diabetes and Digestive and Kidney Diseases, University of Bonn, National Institutes of Health, Karolinska Institutet, La Jolla Institute for Immunology, Centre for Human Drug Research
- APAdriaan P. IJzerman
University of Bonn, Centre for Human Drug Research, Karolinska Institutet, La Jolla Institute for Immunology, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases
- KAKenneth A. Jacobson
La Jolla Institute for Immunology, Karolinska Institutet, Centre for Human Drug Research, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, University of Bonn
- JLJoel Linden
National Institute of Diabetes and Digestive and Kidney Diseases, University of Bonn, Karolinska Institutet, Centre for Human Drug Research, National Institutes of Health, La Jolla Institute for Immunology
- CEChrista E. Müller
Topics & keywords
- Adenosine receptor
- Adenosine
- Receptor
- Pharmacology
- Allosteric regulation
- Medicine
- Neuroscience
- Biology