Vitamin D supplementation in early childhood and risk of type 1 diabetes: a systematic review and meta-analysis

To assess whether vitamin D supplementation in infancy reduces the risk of type 1 diabetes in later life.

This was a systematic review and meta-analysis using Medline, Embase, Cinahl, Cochrane Central Register of Controlled Trials and reference lists of retrieved articles. The main outcome measure was development of type 1 diabetes. Controlled trials and observational studies that had assessed the effect of vitamin D supplementation on risk of developing type 1 diabetes were included in the analysis.