New Comprehensive Cytogenetic Scoring System for Primary Myelodysplastic Syndromes (MDS) and Oligoblastic Acute Myeloid Leukemia After MDS Derived From an International Database Merge
Apple (Israel) · University of Göttingen
Abstract
PURPOSE: The karyotype is a strong independent prognostic factor in myelodysplastic syndromes (MDS). Since the implementation of the International Prognostic Scoring System (IPSS) in 1997, knowledge concerning the prognostic impact of abnormalities has increased substantially. The present study proposes a new and comprehensive cytogenetic scoring system based on an international data collection of 2,902 patients. PATIENTS AND METHODS: Patients were included from the German-Austrian MDS Study Group (n = 1,193), the International MDS Risk Analysis Workshop (n = 816), the Spanish Hematological Cytogenetics Working Group (n = 849), and the International Working Group on MDS Cytogenetics (n = 44) databases.…
Citation impact
- FWCI
- 37.79
- Percentile
- 100%
- References
- 36
Authors
28Topics & keywords
- International Prognostic Scoring System
- Medicine
- Myelodysplastic syndromes
- Internal medicine
- Hazard ratio
- Cytogenetics
- Oncology
- Myeloid leukemia
- No poverty