articleNucleic Acids ResearchNov 29, 2012GOLD OA

D2P2: database of disordered protein predictions

MEMatt E. OatesPRPedro RomeroTITakashi IshidaMGMohamed GhalwashMJMarcin J. Mizianty

Indiana University – Purdue University Indianapolis · HUN-REN Research Centre for Natural Sciences · +3 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

We present the Database of Disordered Protein Prediction (D(2)P(2)), available at http://d2p2.pro (including website source code). A battery of disorder predictors and their variants, VL-XT, VSL2b, PrDOS, PV2, Espritz and IUPred, were run on all protein sequences from 1765 complete proteomes (to be updated as more genomes are completed). Integrated with these results are all of the predicted (mostly structured) SCOP domains using the SUPERFAMILY predictor. These disorder/structure annotations together enable comparison of the disorder predictors with each other and examination of the overlap between disordered predictions and SCOP domains on a large scale. D(2)P(2) will increase our understanding of the…

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Topics & keywords

Topics
Keywords
  • Biology
  • Context (archaeology)
  • Genome
  • Proteome
  • Download
  • Parsing
  • Set (abstract data type)
  • Source code
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