ZDOCK server: interactive docking prediction of protein–protein complexes and symmetric multimers
Boston University · University of Massachusetts Chan Medical School
Abstract
SUMMARY: Protein-protein interactions are essential to cellular and immune function, and in many cases, because of the absence of an experimentally determined structure of the complex, these interactions must be modeled to obtain an understanding of their molecular basis. We present a user-friendly protein docking server, based on the rigid-body docking programs ZDOCK and M-ZDOCK, to predict structures of protein-protein complexes and symmetric multimers. With a goal of providing an accessible and intuitive interface, we provide options for users to guide the scoring and the selection of output models, in addition to dynamic visualization of input structures and output docking models. This server enables the…
Citation impact
- FWCI
- 43.11
- Percentile
- 100%
- References
- 17
Authors
6- BGBrian G. PierceCorresponding
Boston University, University of Massachusetts Chan Medical School
- KWKevin Wiehe
Boston University, University of Massachusetts Chan Medical School
- HHHowook Hwang
Boston University, University of Massachusetts Chan Medical School
- BKBong‐Hyun Kim
Boston University, University of Massachusetts Chan Medical School
- TVThom Vreven
Boston University, University of Massachusetts Chan Medical School
Topics & keywords
- Docking (animal)
- Computer science
- Visualization
- Macromolecular docking
- Protein–protein interaction
- Protein structure
- Computational biology
- Distributed computing