Association Between Serum 25-Hydroxyvitamin D Level and Upper Respiratory Tract Infection in the Third National Health and Nutrition Examination Survey
Boston Children's Museum · Massachusetts General Hospital · +3 more institutions
Abstract
Recent studies suggest a role for vitamin D in innate immunity, including the prevention of respiratory tract infections (RTIs). We hypothesize that serum 25-hydroxyvitamin D (25[OH]D) levels are inversely associated with self-reported recent upper RTI (URTI).
We performed a secondary analysis of the Third National Health and Nutrition Examination Survey, a probability survey of the US population conducted between 1988 and 1994. We examined the association between 25(OH)D level and recent URTI in 18 883 participants 12 years and older. The analysis adjusted for demographics and clinical factors (season, body mass index, smoking history, asthma, and chronic obstructive pulmonary disease).
Citation impact
- FWCI
- 51.54
- Percentile
- 100%
- References
- 55
Authors
3- AAAdit A. Ginde
Boston Children's Museum, Massachusetts General Hospital, University of Colorado Denver, Harvard University, Children's Hospital
- JMJonathan M. Mansbach
Massachusetts General Hospital, Harvard University, Children's Hospital, Boston Children's Museum, University of Colorado Denver
- CACarlos A. CamargoCorresponding
Massachusetts General Hospital, University of Colorado Denver, Harvard University, Boston Children's Museum, Children's Hospital
Topics & keywords
- Medicine
- Interquartile range
- National Health and Nutrition Examination Survey
- Odds ratio
- Confidence interval
- Vitamin D and neurology
- Internal medicine
- Respiratory tract infections
- Good health and well-being