The Amygdala Is Enlarged in Children But Not Adolescents with Autism; the Hippocampus Is Enlarged at All Ages
University of California Davis Medical Center · University of California, Davis · +1 more institution
Abstract
Autism is a neurodevelopmental disorder characterized by impairments in reciprocal social interaction, deficits in verbal and nonverbal communication, and a restricted repertoire of activities or interests. We performed a magnetic resonance imaging study to better define the neuropathology of autistic spectrum disorders. Here we report findings on the amygdala and the hippocampal formation. Borders of the amygdala, hippocampus, and cerebrum were defined, and their volumes were measured in male children (7.5-18.5 years of age) in four diagnostic groups: autism with mental retardation, autism without mental retardation, Asperger syndrome, and age-matched typically developing controls. Although there were no…
Citation impact
- FWCI
- 12.91
- Percentile
- 100%
- References
- 68
Authors
9Topics & keywords
- Autism
- Amygdala
- Psychology
- Hippocampus
- Hippocampal formation
- Brain size
- Autism spectrum disorder
- Typically developing