Aqueous Humor Dynamics: A Review

Glaucoma is a family of optic neuropathies which cause irreversible but potentially preventable vision loss. Vision loss in most forms of glaucoma is related to elevated IOP with subsequent injury to the optic nerve. Secretion of aqueous humor and regulation of its outflow are physiologically important processes for maintaining IOP in the normal range. Thus, understanding the complex mechanisms that regulate aqueous humor circulation is essential for management of glaucoma. The two main structures related to aqueous humor dynamics are the ciliary body and the trabecular meshwork (TM). Three mechanisms are involved in aqueous humor formation: diffusion, ultrafiltration and active secretion. Active secretion is…

• RT
  Research to Prevent Blindness

  Award: P30 EY014801
• UO
  University of Miami

  Award: P30 EY014801
• NI
  National Institutes of Health

  Awards: K08 EY016775, P30 EY014801, EY014801