Brief but Efficient: Acute HIV Infection and the Sexual Transmission of HIV
University of St. Gallen · University of North Carolina at Chapel Hill · +1 more institution
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Abstract
Background
We examined whether viral dynamics in the genital tract during the natural history of acute human immunodeficiency virus type 1 (HIV-1) infection could explain efficient heterosexual transmission of HIV.
Methods
We measured HIV-1 concentration in blood and semen samples from patients with acute and long-term HIV-1 infection. We explored the effect of changes in viral dynamics in semen on the probability of transmission per coital act, using a probabilistic model published elsewhere.
Citation impact
667
total citations
- FWCI
- 12.90
- Percentile
- 100%
- References
- 41
Citations per year
Authors
8Topics & keywords
Topics
Keywords
- Semen
- Transmission (telecommunications)
- Immunology
- Sexual transmission
- Viral disease
- Virology
- Medicine
- Sexually transmitted disease
UN Sustainable Development Goals
- Good health and well-being
No related works found for this paper.
Funding
- BSBristol-Myers Squibb
- GGlaxoSmithKline
- NINational Institutes of HealthAwards: P30-AI50410, AI50410
- CFCenter for AIDS Research, University of WashingtonAwards: P30-AI50410, AI50410
- NINational Institute of Allergy and Infectious DiseasesAwards: AI50410, P30-AI50410
- NINational Institute of Diabetes and Digestive and Kidney Diseases
- CFCenter for AIDS Research, University of North Carolina at Chapel HillAward: P30-AI50410