3D Biofabrication Strategies for Tissue Engineering and Regenerative Medicine
Los Alamos National Laboratory · Institute of Micro and Nanotechnology · +9 more institutions
Abstract
Over the past several decades, there has been an ever-increasing demand for organ transplants. However, there is a severe shortage of donor organs, and as a result of the increasing demand, the gap between supply and demand continues to widen. A potential solution to this problem is to grow or fabricate organs using biomaterial scaffolds and a person's own cells. Although the realization of this solution has been limited, the development of new biofabrication approaches has made it more realistic. This review provides an overview of natural and synthetic biomaterials that have been used for organ/tissue development. It then discusses past and current biofabrication techniques, with a brief explanation of the…
Citation impact
- FWCI
- 37.11
- Percentile
- 100%
- References
- 176
Authors
5- PBPiyush Bajaj
Los Alamos National Laboratory, Institute of Micro and Nanotechnology, Bioengineering Center
- RMRyan M. Schweller
Duke University
- AKAli Khademhosseini
Brigham and Women's Hospital, Harvard University, King Abdulaziz University, Kyung Hee University, Harvard–MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology
- JLJennifer L. West
Duke University
- RBRashid BashirCorresponding
University of Illinois Urbana-Champaign, Institute of Micro and Nanotechnology, Bioengineering Center
Topics & keywords
- Biofabrication
- Economic shortage
- Regenerative medicine
- Tissue engineering
- Nanotechnology
- Biotechnology
- Computer science
- Risk analysis (engineering)
Funding
- NSNational Science FoundationAwards: CBET-0939511, 0939511
- EBEmergent Behaviors of Integrated Cellular SystemsAwards: 0939511, CBET-0939511
- NINational Institutes of HealthAwards: EB02597, 0939511, AR057837, CBET-0939511
- DODivision of Chemical, Bioengineering, Environmental, and Transport SystemsAwards: CBET-0939511, 0939511
- MRMedical Research and Materiel Command