reviewArteriosclerosis Thrombosis and Vascular BiologyJan 23, 2009Closed access

Vascular Endothelial Growth Factor

NFNapoleone Ferrara

Bechtel (United States) · Napa Valley College

PubMed
Indexed incrossrefpubmed

Abstract

Vascular endothelial growth factor (VEGF, VEGF-A) is a major regulator of physiological and pathological angiogenesis. Several VEGF inhibitors have been approved by the FDA for the treatment of advanced cancer and neovascular age-related macular degeneration. This brief review provides a historic account of the challenges associated with the discovery of VEGF and the early steps in elucidating the role of this molecule in the regulation of angiogenesis.

Citation impact

1,275
total citations
FWCI
47.49
Percentile
100%
References
30
Citations per year

Authors

1

Topics & keywords

Topics
Keywords
  • Angiogenesis
  • Vascular endothelial growth factor
  • Regulator
  • Macular degeneration
  • VEGF receptors
  • Vascular endothelial growth factor A
  • Medicine
  • Pathological
UN Sustainable Development Goals
  • Good health and well-being
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