reviewHepatologyNov 13, 2015GREEN OA

Antiviral therapy for chronic hepatitis B viral infection in adults: A systematic review and meta‐analysis

University of Michigan · Alaska Native Tribal Health Consortium · +5 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

UNLABELLED: Chronic hepatitis B viral (HBV) infection remains a significant global health problem. Evidence-based guidelines are needed to help providers determine when treatment should be initiated, which medication is most appropriate, and when treatment can safely be stopped. The American Association for the Study of Liver Diseases HBV guideline methodology and writing committees developed a protocol a priori for this systematic review. We searched multiple databases for randomized controlled trials and controlled observational studies that enrolled adults ≥18 years old diagnosed with chronic HBV infection who received antiviral therapy. Data extraction was done by pairs of independent reviewers. We…

Citation impact

543
total citations
FWCI
28.65
Percentile
100%
References
93
Citations per year

Authors

17

Topics & keywords

Keywords
  • Meta-analysis
  • Medicine
  • Chronic hepatitis
  • Antiviral therapy
  • Virology
  • Viral load
  • Hepatitis B
  • Immunology
UN Sustainable Development Goals
  • Good health and well-being
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Funding