Microfluidic Bioprinting of Heterogeneous 3D Tissue Constructs Using Low‐Viscosity Bioink
Harvard–MIT Division of Health Sciences and Technology · Sapienza University of Rome · +6 more institutions
Abstract
A novel bioink and a dispensing technique for 3D tissue-engineering applications are presented. The technique incorporates a coaxial extrusion needle using a low-viscosity cell-laden bioink to produce highly defined 3D biostructures. The extrusion system is then coupled to a microfluidic device to control the bioink arrangement deposition, demonstrating the versatility of the bioprinting technique. This low-viscosity cell-responsive bioink promotes cell migration and alignment within each fiber organizing the encapsulated cells. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online…
Citation impact
- FWCI
- 36.00
- Percentile
- 100%
- References
- 54
Authors
9- CCCristina Colosi
Harvard–MIT Division of Health Sciences and Technology, Sapienza University of Rome, Brigham and Women's Hospital, Innovation Research Center, Harvard University
- SRSu Ryon Shin
Harvard University, Harvard–MIT Division of Health Sciences and Technology, Brigham and Women's Hospital, Innovation Research Center
- VMVijayan Manoharan
Innovation Research Center, Harvard University, Brigham and Women's Hospital, Harvard–MIT Division of Health Sciences and Technology
- SMSolange Massa
Harvard University, Innovation Research Center, Universidad de Los Andes, Chile, Harvard–MIT Division of Health Sciences and Technology, Brigham and Women's Hospital
- MCMarco Costantini
Sapienza University of Rome
Topics & keywords
- 3D bioprinting
- Microfluidics
- Materials science
- Nanotechnology
- Extrusion
- Computer science
- Viscosity
- Tissue engineering