articleDatabaseJan 1, 2015GOLD OA

RegNetwork: an integrated database of transcriptional and post-transcriptional regulatory networks in human and mouse

ZLZhi‐Ping LiuCWCanglin WuHMHongyu MiaoHWHulin Wu

Shandong University · The University of Texas Health Science Center at Houston

PubMed
Indexed incrossrefdoajpubmed

Abstract

Transcriptional and post-transcriptional regulation of gene expression is of fundamental importance to numerous biological processes. Nowadays, an increasing amount of gene regulatory relationships have been documented in various databases and literature. However, to more efficiently exploit such knowledge for biomedical research and applications, it is necessary to construct a genome-wide regulatory network database to integrate the information on gene regulatory relationships that are widely scattered in many different places. Therefore, in this work, we build a knowledge-based database, named 'RegNetwork', of gene regulatory networks for human and mouse by collecting and integrating the documented…

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583
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Authors

4

Topics & keywords

Topics
Keywords
  • Gene regulatory network
  • Computational biology
  • Transcriptional regulation
  • Gene
  • Regulation of gene expression
  • Biology
  • Database
  • Regulatory sequence
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