Advances and Challenges of Liposome Assisted Drug Delivery
University of Newcastle Australia · Hunter Medical Research Institute · +2 more institutions
Abstract
The application of liposomes to assist drug delivery has already had a major impact on many biomedical areas. They have been shown to be beneficial for stabilizing therapeutic compounds, overcoming obstacles to cellular and tissue uptake, and improving biodistribution of compounds to target sites in vivo. This enables effective delivery of encapsulated compounds to target sites while minimizing systemic toxicity. Liposomes present as an attractive delivery system due to their flexible physicochemical and biophysical properties, which allow easy manipulation to address different delivery considerations. Despite considerable research in the last 50 years and the plethora of positive results in preclinical…
Citation impact
- FWCI
- 43.13
- Percentile
- 100%
- References
- 149
Authors
6- LSLisa Sercombe
University of Newcastle Australia, Hunter Medical Research Institute
- TVTejaswi Veerati
Rice University, The University of Texas MD Anderson Cancer Center
- FMFatemeh Moheimani
University of Newcastle Australia, Hunter Medical Research Institute
- SYSherry Y. Wu
The University of Texas MD Anderson Cancer Center
- AKAnil K. Sood
The University of Texas MD Anderson Cancer Center
Topics & keywords
- Liposome
- Drug delivery
- Biodistribution
- Targeted drug delivery
- Drug
- Pharmacology
- Medicine
- Nanotechnology
- Good health and well-being