reviewThe British Journal of PsychiatryJun 1, 2006Closed access

Brain volume in first-episode schizophrenia

University of North Carolina at Chapel Hill

PubMed
Indexed incrossrefpubmed

Abstract

Background

Studies of people with schizophrenia assessed using magnetic resonance imaging (MRI) usually include patients with first-episode and chronic disease, yet brain abnormalities may be limited to those with chronic schizophrenia.

Aims

To determine whether patients with a first episode of schizophrenia have characteristic brain abnormalities. METHOD: Systematic review and meta-analysis of 66 papers comparing brain volume in patients with a first psychotic episode with volume in healthy controls.

Citation impact

842
total citations
FWCI
29.45
Percentile
100%
References
96
Citations per year

Authors

5

Topics & keywords

Keywords
  • Brain size
  • Schizophrenia (object-oriented programming)
  • Magnetic resonance imaging
  • Medicine
  • Meta-analysis
  • Neuroimaging
  • Psychology
  • Psychosis
UN Sustainable Development Goals
  • Good health and well-being
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