A Randomized Trial of Intensive versus Standard Blood-Pressure Control

A Randomized Trial of Intensive versus Standard Blood-Pressure ControlTo the Editor: Wright et al. (Nov.26 issue) 1 report on the Systolic Blood Pressure Intervention Trial (SPRINT).By focusing on blood-pressure levels, rather than on specific antihypertensive agents, this trial follows a rich heritage of government-funded, noncommercial, randomized trials in hypertension that address major public health issues.The clear differences in outcomes, including lower rates of death among patients who were randomly assigned to intensive treatment than among those assigned to standard treatment, underscore the major impact of implementing this lower blood-pressure target for the appropriate population.Achievement of a…