Antibiotics and the Human Gut Microbiome: Dysbioses and Accumulation of Resistances

The human microbiome is overly exposed to antibiotics, due, not only to their medical use, but also to their utilization in farm animals and crops. Microbiome composition can be rapidly altered by exposure to antibiotics, with potential immediate effects on health, for instance through the selection of resistant opportunistic pathogens that can cause acute disease. Microbiome alterations induced by antibiotics can also indirectly affect health in the long-term. The mutualistic microbes in the human body interact with many physiological processes, and participate in the regulation of immune and metabolic homeostasis. Therefore, antibiotic exposure can alter many basic physiological equilibria, promoting…

• MD
  Ministerio de Economía y Competitividad

  Award: SAF2012-31187
• GV
  Generalitat Valenciana

  Award: UGP-14-167
• FP
  Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana