articleEuropean Respiratory JournalJan 31, 2016BRONZE OA

Treatable traits: toward precision medicine of chronic airway diseases

Centro de Investigación Biomédica en Red de Enfermedades Respiratorias · Hospital Clínic de Barcelona · +19 more institutions

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Abstract

Asthma and chronic obstructive pulmonary disease (COPD) are two prevalent chronic airway diseases that have a high personal and social impact. They likely represent a continuum of different diseases that may share biological mechanisms (i.e. endotypes), and present similar clinical, functional, imaging and/or biological features that can be observed (i.e. phenotypes) which require individualised treatment. Precision medicine is defined as "treatments targeted to the needs of individual patients on the basis of genetic, biomarker, phenotypic, or psychosocial characteristics that distinguish a given patient from other patients with similar clinical presentations". In this Perspective, we propose a precision…

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