Treatable traits: toward precision medicine of chronic airway diseases
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias · Hospital Clínic de Barcelona · +19 more institutions
Abstract
Asthma and chronic obstructive pulmonary disease (COPD) are two prevalent chronic airway diseases that have a high personal and social impact. They likely represent a continuum of different diseases that may share biological mechanisms (i.e. endotypes), and present similar clinical, functional, imaging and/or biological features that can be observed (i.e. phenotypes) which require individualised treatment. Precision medicine is defined as "treatments targeted to the needs of individual patients on the basis of genetic, biomarker, phenotypic, or psychosocial characteristics that distinguish a given patient from other patients with similar clinical presentations". In this Perspective, we propose a precision…
Citation impact
- FWCI
- 69.55
- Percentile
- 100%
- References
- 75
Authors
12- ÀAÀlvar AgustíCorresponding
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias, Hospital Clínic de Barcelona, Consorci Institut D'Investigacions Biomediques August Pi I Sunyer, Universitat de Barcelona
- EHElisabeth H. Bel
University of Amsterdam
- MTMike Thomas
University of Southampton
- CVClaus Vogelmeier
Philipps University of Marburg, German Center for Lung Research
- GBGuy Brusselle
Ghent University Hospital, Erasmus MC
Topics & keywords
- Medicine
- COPD
- Precision medicine
- Asthma
- Psychosocial
- Intensive care medicine
- Airway
- Pulmonary disease
Funding
- FCFundació Catalana de Pneumologia
- NINational Institute for Health and Care Research
- INInstitut National de la Santé et de la Recherche Médicale
- UPUniversité Paris-Sud
- SESociedad Española de Neumología y Cirugía TorácicaAwards: PI065/2013, PI192/2012, PI065/2013
- IDInstituto de Salud Carlos IIIAward: PI12/01117