reviewMolecular OncologyJan 28, 2016BRONZE OA

Circulating tumor cell technologies

MMMeghaan M. FerreiraVCVishnu C. RamaniSSStefanie S. Jeffrey

Stanford University · Stanford Medicine

PubMed
Indexed incrossrefdoajpubmed

Abstract

Circulating tumor cells, a component of the "liquid biopsy", hold great potential to transform the current landscape of cancer therapy. A key challenge to unlocking the clinical utility of CTCs lies in the ability to detect and isolate these rare cells using methods amenable to downstream characterization and other applications. In this review, we will provide an overview of current technologies used to detect and capture CTCs with brief insights into the workings of individual technologies. We focus on the strategies employed by different platforms and discuss the advantages of each. As our understanding of CTC biology matures, CTC technologies will need to evolve, and we discuss some of the present…

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516
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Authors

3

Topics & keywords

Topics
Keywords
  • Circulating tumor cell
  • Liquid biopsy
  • Computer science
  • Tumor cells
  • Computational biology
  • Biology
  • Cancer research
  • Cancer
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