reviewChemical Society ReviewsJan 1, 2016HYBRID OA

Catalytic asymmetric dearomatization (CADA) reactions of phenol and aniline derivatives

Chinese Academy of Sciences · Shanghai Institute of Organic Chemistry · +4 more institutions

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Abstract

Phenols are widely used as starting materials in both industrial and academic society. Dearomatization reactions of phenols provide an efficient way to construct highly functionalized cyclohexadienones. The main challenge to make them asymmetric by catalytic methods is to control the selectivity while overcoming the loss of aromaticity. In this tutorial review, an up to date summary of recent progress in CADA reactions of phenol and aniline derivatives is presented.

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