reviewFrontiers in MicrobiologyFeb 9, 2016GOLD OA

Porphyromonas gingivalis: An Overview of Periodontopathic Pathogen below the Gum Line

KYKah Yan HowKPKeang Peng SongKCKok‐Gan Chan

University of Malaya · Monash University Malaysia

PubMed
Indexed incrossrefdoajpubmed

Abstract

Periodontal disease represents a group of oral inflammatory infections initiated by oral pathogens which exist as a complex biofilms on the tooth surface and cause destruction to tooth supporting tissues. The severity of this disease ranges from mild and reversible inflammation of the gingiva (gingivitis) to chronic destruction of connective tissues, the formation of periodontal pocket and ultimately result in loss of teeth. While human subgingival plaque harbors more than 500 bacterial species, considerable research has shown that Porphyromonas gingivalis, a Gram-negative anaerobic bacterium, is the major etiologic agent which contributes to chronic periodontitis. This black-pigmented bacterium produces a…

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Topics & keywords

Topics
Keywords
  • Porphyromonas gingivalis
  • Virulence
  • Gingivitis
  • Microbiology
  • Biofilm
  • Pathogenesis
  • Periodontitis
  • Pathogen
UN Sustainable Development Goals
  • Life in Land
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