articleBioinformaticsSep 22, 2015BRONZE OA

Approximately independent linkage disequilibrium blocks in human populations

TBTomaz BerisaJKJoseph K. Pickrell

New York Genome Center · Columbia University

PubMed
Indexed incrossrefdoajpubmed

Abstract

UNLABELLED: We present a method to identify approximately independent blocks of linkage disequilibrium in the human genome. These blocks enable automated analysis of multiple genome-wide association studies. AVAILABILITY AND IMPLEMENTATION: code: http://bitbucket.org/nygcresearch/ldetect; data: http://bitbucket.org/nygcresearch/ldetect-data. CONTACT: tberisa@nygenome.org SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

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Topics & keywords

Topics
Keywords
  • Linkage disequilibrium
  • Disequilibrium
  • Linkage (software)
  • Computer science
  • Human genome
  • Genome
  • Genetic association
  • Computational biology
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