Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems
Iran University of Medical Sciences · Sharif University of Technology · +17 more institutions
Abstract
New achievements in the realm of nanoscience and innovative techniques of nanomedicine have moved micro/nanoparticles (MNPs) to the point of becoming actually useful for practical applications in the near future. Various differences between the extracellular and intracellular environments of cancerous and normal cells and the particular characteristics of tumors such as physicochemical properties, neovasculature, elasticity, surface electrical charge, and pH have motivated the design and fabrication of inventive "smart" MNPs for stimulus-responsive controlled drug release. These novel MNPs can be tailored to be responsive to pH variations, redox potential, enzymatic activation, thermal gradients, magnetic…
Citation impact
- FWCI
- 93.65
- Percentile
- 100%
- References
- 553
Authors
17- MKMahdi Karimi
Iran University of Medical Sciences
- AGAmir Ghasemi
Sharif University of Technology
- PSParham Sahandi Zangabad
Sharif University of Technology
- RRReza Rahighi
Chemistry and Chemical Engineering Research Center of Iran
- SMSeyed Masoud Moosavi Basri
Sharif University of Technology, Active Space Technologies (Portugal), Shahid Beheshti University
Topics & keywords
- Drug delivery
- Gene delivery
- Drug
- Nanoparticle
- Nanotechnology
- Stimulus (psychology)
- Chemistry
- Pharmacology
- Good health and well-being