Large-Scale Applications of Amide Coupling Reagents for the Synthesis of Pharmaceuticals
Gilead Sciences (United States) · Pfizer (United States)
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Abstract
This review showcases various coupling reagents which have been implemented specifically for large-scale amide synthesis via the condensation of an acid and amine, while highlighting the benefits and drawbacks of each reagent on an industrial scale.
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793
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- 18.97
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- 100%
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Authors
3Topics & keywords
Topics
Keywords
- Reagent
- Amide
- Amine gas treating
- Combinatorial chemistry
- Scale (ratio)
- Coupling (piping)
- Chemistry
- Condensation
UN Sustainable Development Goals
- Industry, innovation and infrastructure
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