reviewAnnual Review of Genomics and Human GeneticsJun 30, 2016HYBRID OA

Advancements in Next-Generation Sequencing

HudsonAlpha Institute for Biotechnology

PubMed
Indexed incrossrefpubmed

Abstract

The term next-generation sequencing is almost a decade old, but it remains the colloquial way to describe highly parallel or high-output sequencing methods that produce data at or beyond the genome scale. Since the introduction of these technologies, the number of applications and methods that leverage the power of genome-scale sequencing has increased at an exponential pace. This review highlights recent concepts, technologies, and methods from next-generation sequencing to illustrate the breadth and depth of the applications and research areas that are driving progress in genomics.

Citation impact

645
total citations
FWCI
27.33
Percentile
100%
References
133
Citations per year

Authors

2

Topics & keywords

Keywords
  • DNA sequencing
  • Leverage (statistics)
  • Genomics
  • Pace
  • Data science
  • Hybrid genome assembly
  • Cancer genome sequencing
  • Genome
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