Nanotechnology-Based Drug Delivery Systems for Photodynamic Therapy of Cancer: A Review

Photodynamic therapy (PDT) is a promising alternative approach for improved cancer treatment. In PDT, a photosensitizer (PS) is administered that can be activated by light of a specific wavelength, which causes selective damage to the tumor and its surrounding vasculature. The success of PDT is limited by the difficulty in administering photosensitizers (PSs) with low water solubility, which compromises the clinical use of several molecules. Incorporation of PSs in nanostructured drug delivery systems, such as polymeric nanoparticles (PNPs), solid lipid nanoparticles (SLNs), nanostructured lipid carriers (NLCs), gold nanoparticles (AuNPs), hydrogels, liposomes, liquid crystals, dendrimers, and cyclodextrin is…

• FD
  Fundação de Amparo à Pesquisa do Estado de São Paulo

  Award: 2014/
• CN
  Conselho Nacional de Desenvolvimento Científico e Tecnológico
• UE
  Universidade Estadual Paulista