Lactobacillus plantarum strain maintains growth of infant mice during chronic undernutrition

Microbiota and infant development Malnutrition in children is a persistent challenge that is not always remedied by improvements in nutrition. This is because a characteristic community of gut microbes seems to mediate some of the pathology. Human gut microbes can be transplanted effectively into germ-free mice to recapitulate their associated phenotypes. Using this model, Blanton et al. found that the microbiota of healthy children relieved the harmful effects on growth caused by the microbiota of malnourished children. In infant mammals, chronic undernutrition results in growth hormone resistance and stunting. In mice, Schwarzer et al. showed that strains of Lactobacillus plantarum in the gut microbiota…

• FI
  Fondation Innovations en Infectiologie
• GA
  Grantová Agentura České Republiky

  Award: P303-12-0535
• CN
  Centre National de la Recherche Scientifique

  Award: CNRS/AVCR 13-14
• HE
  H2020 European Research Council

  Award: FP7/2007-2013-N�309704