Aptamer-integrated DNA nanostructures for biosensing, bioimaging and cancer therapy
Hunan University · Theranostics (New Zealand) · +3 more institutions
Abstract
The combination of nanostructures with biomolecules leading to the generation of functional nanosystems holds great promise for biotechnological and biomedical applications. As a naturally occurring biomacromolecule, DNA exhibits excellent biocompatibility and programmability. Also, scalable synthesis can be readily realized through automated instruments. Such unique properties, together with Watson-Crick base-pairing interactions, make DNA a particularly promising candidate to be used as a building block material for a wide variety of nanostructures. In the past few decades, various DNA nanostructures have been developed, including one-, two- and three-dimensional nanomaterials. Aptamers are single-stranded…
Citation impact
- FWCI
- 36.21
- Percentile
- 100%
- References
- 152
Authors
6- HMHong‐Min Meng
Hunan University, Theranostics (New Zealand), Max Planck Institute for Molecular Biomedicine, State Key Laboratory of Chemobiosensing and Chemometrics, Henan Normal University
- HLHui Liu
Hunan University, Theranostics (New Zealand), Max Planck Institute for Molecular Biomedicine, State Key Laboratory of Chemobiosensing and Chemometrics
- HKHailan Kuai
Hunan University, Theranostics (New Zealand), Max Planck Institute for Molecular Biomedicine, State Key Laboratory of Chemobiosensing and Chemometrics
- RPRuizi Peng
Hunan University, Theranostics (New Zealand), Max Planck Institute for Molecular Biomedicine, State Key Laboratory of Chemobiosensing and Chemometrics
- LMLiuting Mo
Hunan University, Theranostics (New Zealand), Max Planck Institute for Molecular Biomedicine, State Key Laboratory of Chemobiosensing and Chemometrics
Topics & keywords
- Aptamer
- Biosensor
- Nanotechnology
- Cancer therapy
- DNA
- Nanostructure
- Cancer
- Chemistry