Uptake and Accumulation of Polystyrene Microplastics in Zebrafish ( Danio rerio ) and Toxic Effects in Liver
Nanjing University · State Key Laboratory of Pollution Control and Resource Reuse · +1 more institution
Abstract
Microplastics have become emerging contaminants, causing widespread concern about their potential toxic effects. In this study, the uptake and tissue accumulation of polystyrene microplastics (PS-MPs) in zebrafish were detected, and the toxic effects in liver were investigated. The results showed that after 7 days of exposure, 5 μm diameter MPs accumulated in fish gills, liver, and gut, while 20 μm diameter MPs accumulated only in fish gills and gut. Histopathological analysis showed that both 5 μm and 70 nm PS-MPs caused inflammation and lipid accumulation in fish liver. PS-MPs also induced significantly increased activities of superoxide dismutase and catalase, indicating that oxidative stress was induced…
Citation impact
- FWCI
- 36.87
- Percentile
- 100%
- References
- 44
Authors
8- YLYifeng LuCorresponding
Nanjing University, State Key Laboratory of Pollution Control and Resource Reuse
- YZYan Zhang
State Key Laboratory of Pollution Control and Resource Reuse, Nanjing University
- YDYongfeng Deng
Nanjing University, State Key Laboratory of Pollution Control and Resource Reuse
- WJWei Jiang
State Key Laboratory of Pollution Control and Resource Reuse, Nanjing University
- YZYanping Zhao
Nanjing Normal University
Topics & keywords
- Microplastics
- Zebrafish
- Gill
- Catalase
- Danio
- Oxidative stress
- Superoxide dismutase
- Toxicity
Funding
- NNNational Natural Science Foundation of ChinaAwards: 21407076, 21507058
- MOMinistry of Education of the People's Republic of ChinaAward: 20130091120012
- MOMinistry of Science and Technology of the People's Republic of ChinaAward: 2014BAC08B07
- NSNatural Science Foundation of Jiangsu ProvinceAward: BK20130559