reviewChemical ReviewsAug 7, 2015Closed access

Iron Oxide Based Nanoparticles for Multimodal Imaging and Magnetoresponsive Therapy

Kookmin University · Yonsei University · +3 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

The development of magnetic iron oxide nanoparticles as magnetic resonance (MR) imaging agents for sensitive and accurate diagnosis through inorganic materials design and their synergistic integration with other imaging modalities is reviewed. Modulation of the size, composition, and shape allows magnetic nanoparticles to fit with their intended purposes, such as MRI imaging, thermal ablation, hyperthermia, combination therapy, and drug deliver. Specifically, magnetic nanoparticles that are synergistically combined with other useful materials have been explored as nanocarriers to regulate the delivery of drugs or genes into the target area as well as specific probes for a variety of imaging modalities, such as…

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