Neuroinflammation: the devil is in the details

Abstract There is significant interest in understanding inflammatory responses within the brain and spinal cord. Inflammatory responses that are centralized within the brain and spinal cord are generally referred to as ‘neuroinflammatory’. Aspects of neuroinflammation vary within the context of disease, injury, infection, or stress. The context, course, and duration of these inflammatory responses are all critical aspects in the understanding of these processes and their corresponding physiological, biochemical, and behavioral consequences. Microglia, innate immune cells of the CNS , play key roles in mediating these neuroinflammatory responses. Because the connotation of neuroinflammation is inherently…

• NI
  National Institute on Aging

  Award: R01‐AG‐033028