Task-free MRI predicts individual differences in brain activity during task performance

Tavor, Ido; Jones, Ōiwi Parker; Mars, Rogier B.; Smith, Stephen M.; Behrens, Timothy E.J.; Jbabdi, Saâd

doi:10.1126/science.aad8127

articleScienceApr 7, 2016GREEN OA

Task-free MRI predicts individual differences in brain activity during task performance

ITIdo Tavor ŌPŌiwi Parker Jones RBRogier B. Mars SMStephen M. Smith TETimothy E.J. Behrens

Sheba Medical Center · John Radcliffe Hospital · +3 more institutions

PubMed

Indexed incrossrefpubmed

Abstract

When asked to perform the same task, different individuals exhibit markedly different patterns of brain activity. This variability is often attributed to volatile factors, such as task strategy or compliance. We propose that individual differences in brain responses are, to a large degree, inherent to the brain and can be predicted from task-independent measurements collected at rest. Using a large set of task conditions, spanning several behavioral domains, we train a simple model that relates task-independent measurements to task activity and evaluate the model by predicting task activation maps for unseen subjects using magnetic resonance imaging. Our model can accurately predict individual differences in…

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Topics & keywords

Topics

Keywords

Task (project management)
Brain activity and meditation
Functional magnetic resonance imaging
Set (abstract data type)
Computer science
Brain mapping
Neuroimaging
Magnetic resonance imaging

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