reviewAnnals of SurgeryDec 2, 2015Closed access

Comparative Short-term Benefits of Laparoscopic Liver Resection

University of Córdoba · Iwate Medical University · +5 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

Objective

To perform a systematic review of worldwide literature on laparoscopic liver resections (LLR) and compare short-term outcomes against open liver resections (OLR) by meta-analyses. SUMMARY BACKGROUND DATA: There are no updated pooled data since 2009 about the current status and short-term outcomes of LLR worldwide. PATIENTS AND METHODS: All English language publications on LLR were screened. Descriptive worldwide data and short-term outcomes were obtained. Separate analyses were performed for minor-only and major-only resection series, and series in which minor/major resections were not differentiated. Apparent case duplications were excluded.

Results

A set of 463 published manuscripts were reviewed. One hundred seventy-nine single-center series were identified that accounted for 9527 LLR cases worldwide. Minor-only, major-only, and combined major-minor series were 61, 18, and 100, respectively, including 32, 8, and 43 comparative series, respectively. Of the total 9527 LLR cases reported, 6190 (65%) were for malignancy and 3337 (35%) were for benign indications. There were 37 deaths reported (mortality rate = 0.4%). From the meta-analysis comparing case-matched LLR to OLR (N = 2900 cases), there was no increased mortality and significantly less complications, transfusions, blood loss, and hospital stay observed in LLR vs OLR.

Citation impact

729
total citations
FWCI
26.68
Percentile
100%
References
189
Citations per year

Authors

5

Topics & keywords

Keywords
  • Medicine
  • Malignancy
  • Surgery
  • Blood loss
  • General surgery
  • Internal medicine
UN Sustainable Development Goals
  • Good health and well-being
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