German Outbreak of Escherichia coli O104:H4 Associated with Sprouts

Buchholz, Udo; Bernard, Helen; Werber, Dirk; Böhmer, Merle M.; Remschmidt, Cornelius; Wilking, Hendrik; Deleré, Yvonne; Heiden, Matthias an der; Adlhoch, Cornelia; Dreesman, Johannes; Ehlers, Joachim; Ethelberg, Steen; Faber, Mirko; Frank, Christina; Fricke, Gerd; Greiner, Matthias; Höhle, Michael; Ivarsson, Sofie; Jark, Uwe; Kirchner, Markus; Koch, Judith; Krause, Gérard; Luber, Petra; Rosner, Bettina; Stark, Klaus; Kühne, Michael

doi:10.1056/nejmoa1106482

articleNew England Journal of MedicineOct 26, 2011BRONZE OA

German Outbreak of Escherichia coli O104:H4 Associated with Sprouts

UBUdo Buchholz HBHelen Bernard DWDirk Werber MMMerle M. Böhmer CRCornelius Remschmidt

Robert Koch Institute

PubMed

Indexed incrossrefpubmed

Abstract

Background

A large outbreak of the hemolytic-uremic syndrome caused by Shiga-toxin-producing Escherichia coli O104:H4 occurred in Germany in May 2011. The source of infection was undetermined.

Methods

We conducted a matched case-control study and a recipe-based restaurant cohort study, along with environmental, trace-back, and trace-forward investigations, to determine the source of infection.

Citation impact

715

total citations

FWCI: 46.66
Percentile: 100%
References: 11

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Authors

26

Topics & keywords

Topics

Keywords

Outbreak
Medicine
Odds ratio
Diarrhea
Bloody diarrhea
Confidence interval
Food poisoning
Environmental health

UN Sustainable Development Goals

Good health and well-being

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