articleJournal of Medicinal ChemistryOct 12, 2012GREEN OA

Organosilicon Molecules with Medicinal Applications

University of California, Davis

PubMed
Indexed incrossrefdatacitepubmed

Abstract

The incorporation of silicon and synthesis of organosilicon small molecules provide unique opportunities for medicinal applications. The biological investigation of organosilicon small molecules is particularly interesting because of differences in their chemical properties that can contribute to enhanced potency and improved pharmacological attributes. Applications such as inhibitor design, imaging, drug release technology, and mapping inhibitor binding are discussed.

Citation impact

1,109
total citations
FWCI
12.62
Percentile
100%
References
109
Citations per year

Authors

2

Topics & keywords

Keywords
  • Organosilicon
  • Chemistry
  • Small molecule
  • Molecule
  • Drug discovery
  • Combinatorial chemistry
  • Nanotechnology
  • Drug
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