articleBMC BioinformaticsApr 19, 2016GOLD OA

Growthcurver: an R package for obtaining interpretable metrics from microbial growth curves

SIB Swiss Institute of Bioinformatics · University of Zurich · +2 more institutions

PubMed
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Abstract

Background

Plate readers can measure the growth curves of many microbial strains in a high-throughput fashion. The hundreds of absorbance readings collected simultaneously for hundreds of samples create technical hurdles for data analysis.

Results

Growthcurver summarizes the growth characteristics of microbial growth curve experiments conducted in a plate reader. The data are fitted to a standard form of the logistic equation, and the parameters have clear interpretations on population-level characteristics, like doubling time, carrying capacity, and growth rate.

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Funding