Photochemical Approaches to Complex Chemotypes: Applications in Natural Product Synthesis
University of Michigan · Boston University
Abstract
The use of photochemical transformations is a powerful strategy that allows for the formation of a high degree of molecular complexity from relatively simple building blocks in a single step. A central feature of all light-promoted transformations is the involvement of electronically excited states, generated upon absorption of photons. This produces transient reactive intermediates and significantly alters the reactivity of a chemical compound. The input of energy provided by light thus offers a means to produce strained and unique target compounds that cannot be assembled using thermal protocols. This review aims at highlighting photochemical transformations as a tool for rapidly accessing structurally and…
Citation impact
- FWCI
- 91.27
- Percentile
- 100%
- References
- 529
Authors
3Topics & keywords
- Chemistry
- Natural product
- Chemotype
- Excited state
- Photochemistry
- Combinatorial chemistry
- Absorption (acoustics)
- Nanotechnology